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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d7a7633b11fda372e4d608f93f00eea7ce4d2c03efbf964c396333c6c7e5eff' 
  AND token = 'VTGqgXgkcJK/XN3w4C2NtLtx9TsLUJRtN0NOn8pEVUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}