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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e649718ee951f9282e38cc52c681bc6b3cfc72c7323f48a37526e7f0773da9f8' 
  AND token = '/vxmcqbpRxqgAtIgtvKMaP2bE9xwtGoopnKyd414Mto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}