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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e1c8fb404c03bc6b11e0bbd5e5d0b11c791e2d70d63be7dd22de18bf3669951' 
  AND token = 'Eud78/7F1v4/SESGtTwo+BjR6T0zdGUa1tXrdLc0P1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}