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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a8e7e9b778c1a3682403e8b225b72d56db540b7f86681ccc950fe558c0464e' 
  AND token = 'MRdtA2tQWvcdFrHvUbLEH3SMbmbqjk5kk2UqAwrbe+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}