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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '273109d051d9ab8aa9e0ca53cc2f8d9fd217172106c5df3a5327bdf60c2ae511' 
  AND token = 'KzLDVdGKAmO07cPpVr3f1e3Lfs0F91l6xMMnXv46d0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}