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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0012b735f8fd4921ac7297ddc387e29af8b42160b95ea7be5ad603339c483f2' 
  AND token = 'yAgy0S0a/U9su651NGfOcah88YvX9SCYMTyRIwxtsLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}