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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00cb8ff912e84886293c450f7c9baaacb042f2186561503ca1c08edc5d8f0ab1' 
  AND token = 'T+hPvWZex3R/8sIN10p6gcic+q7kwMtlEYT4m3UnByc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}