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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cec41d7bd69fb2d69fbad0792da315b7b5a2c252231ec8285d209b879bcdd6d7' 
  AND token = 'ymZ1AT3XE2plyIrbITiS2UFVFkbn1MLCJ2RZR0d5zz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}