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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68c4dc6c96b8df52604842bf0279ea6668cb8ba03f47eb60e9d6393370388808' 
  AND token = 'XhQDlsLs+GPiHKLD3Ya1/4DbhD2AV14CsI21FLK8MVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}