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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2feeb1a5960c817b6657e2d22c45509b9f6721f0026f752256dd8e47f1fba967' 
  AND token = 'Zp07OA3GIVbKahGKTiVNLs6j0cLH+tQstH0mUPtGdX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}