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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e123ce1b91df0501896289e173ee5b80a47e9b7849cb95d52a1688a1d3e17649' 
  AND token = 'n92TpgUAVpPQp8m1hFER3E5k4YVIRjsHbBtCZWRJ8o0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}