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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81204a10259655f08f06f4eee860a2d654424f9edfff0457ec2277f9b998a42f' 
  AND token = 'yHsbRkcs7vWf6U1OHvuRaxdpHZxAwZtu5L+9j/sHjKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}