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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9091e6258bdf774e98c68c9b76e5ecf81f026ba3a1bdf84864626c147163ae1b' 
  AND token = 'QDi2xWNNVPzBD+qdWjSDlnaOIYozREtTdX7VaCWdP0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}