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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b03adb078d7f3224b60a5d16bd7d4e00d534420dd1c0463c1eb3cc1cfcab61' 
  AND token = '+7X65a7E8Zi7NbWaNCMgsSe1t6p9MA2Vw7mdDmxg2Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}