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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22314deca8a6a4096b11a467d561a0e91eed99e0f0a812b56d2dab92a3963ca' 
  AND token = 'FAsBAiZce0Xn3r6/TCRQfkE25Bin4mNMrMMvU/1MlFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}