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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b40546fc2e98ac1b9465b8da9af7d2a1cc19e25b71629cc2a3d3e3e2bf64201' 
  AND token = 'E1YI30C4nT9gSHv/qefkgMufpIlLtNSOSDPv9q6UG0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}