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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a545d64bd36ebb72097f241f1f16aa8205cad81aa6205336993e40d103095151' 
  AND token = 'ADcnDKrSlL7bsF3APdcU+G+3FbiBT+cNMpKdoUqDgoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}