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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f0973a74aee2cad11202f053d9fd78a2fa46dea4b561d052daff4f72d76e32d' 
  AND token = 'HpGGza2cyAx7vHqUQ5M7DJ7SeyewDqE/ALEgXVDq0Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}