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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57486f5835e00c65f67939413fab7d6f1caacfcf40ab1f6187d17aace4f19acb' 
  AND token = 'wbbO6Zul93OwqrtxKWpQcQKJE1DeNbqq1bPuxV80Ivg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}