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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9a7d9aeecf00d291f4ace870d4769a7a3be0a7129f7c9d44b9164536b7df364' 
  AND token = '0VV1yZqtEC+5OE7Cm3jz4HVEIrTvifGS+4vDOblKfVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}