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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c972c4dd192aee6264c80d84854de16e31c9a8f05535b3eb2ef9ef860b95c5' 
  AND token = 'jKJ0g7eIQtvr4BkpRSuEHpW/hrxmxmIrJu+/JLu8jMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}