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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9361c292bbf2248f167550e4dd69851a0ade6d5282fa936ac16e2a96d1bb486' 
  AND token = 'iwc7YW2p9s/Y2TU4HVX7PL6zG7jsSzJb9RPca/rPWxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}