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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd18003c1df29bde072048c95af60185e3a503f01b410c183e72d643b2ce88db1' 
  AND token = 'dH5FUzG8xThpGOhc2L2fhT3EREERPvUR+l2e9aWhGBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}