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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbe6b6dba34087aaa81c7af772cabf5f53491ea662694ed2cba2812d165f5100' 
  AND token = '2N9O/ADU/UECOZXDwXiLTlvDEeg8n2nG2VO1HIZ+MY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}