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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e730c08ef2b3a8170c394bc7373465e6e44e67e52b555b2b9b5864390093486f' 
  AND token = 'z2gGPzpGcOYPk2KF9PgBYNY7CGs9Mp4m78dYM9Fxe3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}