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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22868811025d9d5701f6256da9cbf3f48726d07fbdf7da9ae077f233a7585e3' 
  AND token = 'KRzVuY/dzjdva5xbhOzDP5es/E/Jxv0mFj88JIEEQr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}