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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '221dc6a0294479b670c513b36bb2ac2bacfc257b41ae9f25d97ddba217915cbc' 
  AND token = 'gvg/CavK0Ork5Hc21AQKMXtgsHQio1+tS4emt/WKr1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}