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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b2bf2572c9470b25155fa77394cf988f4528009102e29f955395c4c0d75b4a' 
  AND token = '9zb67jF8O7dKfCYjOzFgEEGkfzgz+fNOqZBcib6Q8sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}