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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fafa1dbc456b99edfa68191615bb8fa1cda95a35b93d50c68973dd9c5ce3c0e' 
  AND token = 'ZxmxQFJ/u5a+DD12KeZahCy4UARwA+oANQf/vm8vDtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}