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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb9d96357ce7d461aa133062242c3c6e581baf11b79ca7b718533a65c753dfb0' 
  AND token = 'uFJ+Y9QtKXopgsItWpnbk+xzX0+75fwnJkyftwHnqHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}