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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba45f7b1e8d749c3a1b23d52878476f7bde0b73a1643edfd7d683dddf23880e8' 
  AND token = '0AaVpf75OovMJzLs6TXAS01yF0GRilxjq4k8AMOCDmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}