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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9695d53e4b273cc824e25ccfe10ba1bc2a2649f5b2a75df691a84a0941f398e' 
  AND token = 'u60+ESkXkBN7cRVTHsgPqjWBxAG3+IvoqH+rvR4NLEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}