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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '810e5c13e89b934b709304a3518d3db5d5753775a51e9dfd11e09ca8002ffa82' 
  AND token = 'D014XYvAalAWJWAM0oVGnO3wZPbKLCOVQegOarXFhrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}