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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5cf6119604f7815a0ac72be11d6b378775a10b5a6292197b09462b08e01b3e1' 
  AND token = '3nRjH9SVVJ6V5OhWdWkNWVRM9tAkrskYA2foT3qAeHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}