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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8666d83e4272723d6f0a0ee535b63c1397450f8c5f0e67611c3e94615e07abba' 
  AND token = '8eYo9eSfW3cM5td3ixl6ahq9rmS6VKS7rFmaSN4svVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}