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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8627e2406605510c26212bdc58fa0caa1a3e4a61f17adddc65231b19e88339ab' 
  AND token = 'QkExvq19L7TW9Zuzotu4GR1JoPzgI8xgt+wcEuq4Vag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}