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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '600b3b5f590587ed0623e672715b4fe587c7634b11e31f400b727b9f297e6987' 
  AND token = 'IsGPjGfIXIepab+Sy+G6W4JjzoGr5vhACIFC0Epf0jA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}