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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59dd999590276e7d080ba697df8100a77ccd3d964a374a59d23124f402cca2c4' 
  AND token = 'phkv6fDC65M8J6sIQdH+Uy0Ne8XkvCRf4I10CKIAZKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}