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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6c502017ad18dea4c865d5fb39a42fcc7e02798b82249aee19e30fe46e15a2' 
  AND token = 'nlUPjdctZFoG0/vkNSKCtgjkK4eqbLcPZ44+mrPnr58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}