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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edf52640689059b9318248902fd346988c018f9c7bd8afd6572b8349a77a168d' 
  AND token = 'qnN4jtc4e7LB135so8tLEABackUaE76donQObf4S4vY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}