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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65aaea752a867630167bc5c042411b01d775474ef8e71b60505d47c48f9680fc' 
  AND token = 'Mq1y1e4q/HxS7p+HM1d1DZGrajsTJSWp6VnRutONvQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}