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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5d82f515427ec4951fd38cec9c325dea1ccc3094dad85ac3ecd92e41ce91d3' 
  AND token = 'o5U4N7z2ZIN67pcpSSGDE8Jy4+O8ibdVUgtk81cPSDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}