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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65a3c095b64019a9686d0a45e4ece9a93bb6f0550d2f4d03c23f553f4df66cf8' 
  AND token = 'sUzVimSep0IzWZhgR+VBLTEpbyQHaFtO8CTufgci4Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}