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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee673d598bee41d5257c597190aef445163e46ce143e0a104f68d39935e64617' 
  AND token = 'JVK+OiC03WICPMKSzVVQ0pJNPjpuibbuk5lEV/GXcg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}