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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b3a586407294f78f23d2c0564fd25ff7f6c067686b4eb225eea8e333a520726' 
  AND token = 'SnUjQxcKiXOIuSxJ7/UkroYFFdz+A9sv83FUAvcrnqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}