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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f3fe06e9cd2b2728a3e7d9078179040f7cc3765d09c61821e33f8c4aa868f01' 
  AND token = 'fZY6hB5Gng8qpieXpLbdgeDHEgysbLQimTywT69zGSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}