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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d3bc3ff0ef44163738cea0803255de0715656585fbaf2b30ff83926e64f766c' 
  AND token = 'H2CO085RFrILhRHHPE7nuIm/ny9ICLFfG0B9ebvgkcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}