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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2fc83e21590fde4c339d32da94db12ae8d2421baf87837c7da9f1449a798023' 
  AND token = 'FhipwNQLnan7vKInYQbW2fiLNo8uWRDoFpz1UoqJ6Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}