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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e310d4df12d68c3ef03db92ca98b72690d70377573e91bb09f746d644baf2e6' 
  AND token = 'UF2/LGf7gRgGwerfxlRGI5ECk4vUOZ4I6TVNhn/+tFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}