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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b0b252b9d1a0a7778f497c5147800fff06bb7401549d1054c0e95c0131318d' 
  AND token = '/yB7uR2SKVBRK6s7nRDiJE1tt7693DGtPFxE9DXwCUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}